Holo-Seq: single-cell sequencing of holo-transcriptome
نویسندگان
چکیده
منابع مشابه
The Holo-Transcriptome of a Calcified Early Branching Metazoan
Symbiotic interactions are widespread throughout the animal kingdom and are increasingly recognized as an important trait that can shape the evolution of a species. Sponges are widely understood to be the earliest branching clade of metazoans and often contain dense, diverse yet specific microbial communities which can constitute up to 50% of their biomass. These bacterial communities fulfill d...
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We show a system capable of projecting a video scene onto a white-light holographic screen to obtain a kind of image that results in a plane in front of the screen. This holographic screen is mainly a diffractive lens and is constructed by holography. The image plane can be located at any azimuth angle and seen with continuous parallax and without the use of goggles or any special visualization...
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Background: Mammalian preimplantation development is a complex process involving dramatic changes in the transcriptional architecture. However, it is still unclear about the crucial transcriptional network and key hub genes that regulate the proceeding of preimplantation embryos. Materials and Methods: Through single-cell RNAsequencing (RNA-seq) of both human and mouse preimplantation embryos, ...
متن کاملBiological Variation of Holo-Transcobalamin in Elderly
Individuals, Andrew McCaddon, Peter Hudson, Cherie McCracken, Richard Ellis, and Anne McCaddon ( University of Wales College of Medicine, Division of General Practice, Wrexham LL13 7YP, UK; 2 Department of Pathology, Wrexham Maelor Hospital, Wrexham LL13 7TD, UK; 3 University Department of Psychiatry, Royal Liverpool University Hospital, Liverpool L69 3GA, UK; 4 University Hospital of Wales, Ca...
متن کاملHolo-Entropy Based Categorical Data Hierarchical Clustering
Clustering high-dimensional data is a challenging task in data mining, and clustering high-dimensional categorical data is even more challenging because it is more difficult to measure the similarity between categorical objects. Most algorithms assume feature independence when computing similarity between data objects, or make use of computationally demanding techniques such as PCA for numerica...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2018
ISSN: 1474-760X
DOI: 10.1186/s13059-018-1553-7